• How the Direct-to-Patient Approach Can Streamline your Research Study and Trials

    The research process can be an inconvenience and a burden for the patient test subject; currently over 40% of test subjects drop out mid-way through the trial. In traditional research models, study participants travel to a medical facility/study-site for screening, baseline, monitoring, and follow-up visits โ€“ depending on the study design. However, this model increases...

  • Steps to Reduce Missed Deadlines and Unnecessary Costs in Research Studies and Trials

    High cost along with patient recruitment and retention pose major obstacles to conducting clinical trials in the U.S. According to the Tufts Center for the Study of Drug Development (CSDD), it now costs up to $2.6 billion to bring a new drug to market, and according to a study by the Center for Information and...

  • Fox Insight: Driving Discovery with the Patient Voice

    Patient reported outcomes (PRO) data complements traditional clinical research with scale & accessibility, as well as patient-centricity. The Fox Insight (FI) study aims to gather the worldโ€™s largest dataset on the day-to-day experience of living with PD, from 125,00 participants across the globe. This comprehensive dataset holds the power to help researchers better understand patientsโ€™...

  • Gene Therapy for HD: Sorting Truth from Hype

    Edith Pfister, Ph.D., Assistant Professor, University of Massachusetts Medical This talk will cover the basics of therapies designed to lower huntingtin: what do we know and what donโ€™t we know. It will introduce the basic mechanisms of huntingtin lowering and gene therapy. The goal is to introduce the language of huntingtin lowering and of gene...

  • Lessons Learned from being at the First Wave of the Covid-19 Epidemic in the US

      Hilary Godwin, Ph.D., Dean, University of Washington School of Public Health and Professor in the Department of Environmental & Occupational Health Sciences In early March 2020, Seattle was considered to be a โ€œhot spotโ€ for the COVID-19 epidemic in the United States. A month later, Washington was one of the first states to have...

  • Navigating the Pandemic: A COVID-19 Discussion with the Infectious Disease Community

    Over the past twenty years, the world has faced several infectious disease outbreaks including; Ebola, Influenza A (H1N1), SARS, MERS, Zika virus and now COVID-19. With over 200k deaths worldwide, COVID-19 has brought an enormous strain on our health resources, but also has had a massive impact on human health and the economy. Join infectious...

  • AI and Digital Health Accelerating Rare Disease Clinical Research Powered by Patients

    Harsha Rajasimha, MS, PhD, Founder, Jeeva Informatics Solutions, Inc.; Founder and Chairman, IndoUSrare; Co-Director, Rare Diseases Systems Biology Initiative, George Mason University After losing a child to a rare congenital disease, Dr. Rajasimha became determined to apply his clinical genomics data research experience to develop solutions to help accelerate clinical research leading to faster cures...

  • PFE-001: A Novel Non-Covalent Modulator of Hemoglobin Improves Anemia and Reduces Sickling in a Mouse Model of Sickle Cell Disease

    Kelly M. Knee, PhD, Senior Principal Scientist, Rare Disease Researcher Unit, Pfizer Sickle cell disease is a severe genetic disorder caused by a single point mutation on the ฮฒ-chain of adult hemoglobin (Hb A), ฮฒ6 Gluโ†’Val (Hb S). Numerous small molecules which covalently bind to Hb S have been evaluated clinically, however, the molecules that...

  • Navigating the Pandemic: How will COVID-19 change R&D?

    COVID-19 has put the biopharma industry into a tailspin – big pharma, biotech and small startups are all emerging in the development of a treatment and vaccine for this pandemic. Will COVID-19 change the current R&D landscape and create a new norm for the biopharma industry? Moderator: Joan Koerber-Walker President and CEO, Arizona BioIndustry Association...

  • The Journey from Patient to Advocate to Leader: Changing the Clinical Research Game

    Rob Long, Executive Director, Uplifting Athletes I will talk about my journey from Division I football and top NFL prospect to cancer patient. My experience of undergoing chemo and radiation and fighting through a battle with brain cancer has enabled me to leverage my story to make a difference in the lives of those affected...

  • COVID-19: Navigating the Pandemic: – How with COVID-19 effect research studies and clinical trials?

    COVID-19 has spread to more than 60 countries, causing tens of thousands of illnesses and thousands of deaths. Pharma companies, biotechs, governments, academic institutions, nonprofits and others are all racing to develop a treatment, a cure and a vaccine. Moderator: Craig Lipset Independent Advisor, Former Head of Clinical Innovation, Pfizer Panelists: Brian Neman CEO and...

  • Biospecimen Donation: Personal Journey of a Family and Genetic Diagnostic Lab Advancing Biomedical Research

    Speakers: Sarah Gray, Author, A Life Everlasting: The Extraordinary Story of One Boyโ€™s Gift to Medical Science Arupa Ganguly, PhD, Professor of Genetics, Perelman School of Medicine, University of Pennsylvania Amanda Effres, Head of Feasibility & Study Design, Sanguine Author Sarah Gray shares her story of how she anonymously donated her infant sonโ€™s post-mortem tissue...

  • Implementing AI: The Effects of AI in Drug Development

    Join our distinguished Novartis speaker, Shruthi Bharadwaj, PhD as she speaks about her experience in AI including: With the costs to commercialize a new drug is dramatically increasing to over $2 billion, AI brings the opportunity to assist pharma companies to bring new drugs and therapies to the market faster. However, the evolution of AI...

  • Simplifying Patient Participation

      Research depends on samples from patients and healthy volunteers. However, obtaining biospecimens from human subjects can be a challenge for researchers and patients alike. Home-based specimen collection directly connects patients to researchers, while alleviating the burden of travel to secondary sites. Using this approach, researchers efficiently collect patient samples in the comfort of their...

  • Biobanking Today: Facebook, Crypto, Artificial Intelligence

      Sanguine partners with patients and leverages their health data to accelerate your research for their condition. By working together with patients directly, Sanguine is able to perform home visits and to easily retrieve medical records on their behalf. 500+ completed studies. 20/40 top pharma. 30,000+ patients. Transcript Brian Neiman: My name is Brian Neiman...

  • Forging a Path for Early Clinical Development in Sickle Cell Disease

    Distinguished Pfizer researchers David Beidler and Debra Pittman share their experience in Sickle Cell Disease including: Using longitudinal biomarker data from early clinical development decision in sickle cell disease (SCD) Building the patient perspective into clinical trials: development of the vaso-occlusive crisis (VOC) day endpoint through the use of the electronic patient-reported outcomes (ePRO) Bring...