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Why You Should Break Up with Your Biobank

The initial excitement and growth of biobanks worldwide has faced several challenges related to logistics, ethics, and utility,1,2 which call into question the long-term feasibility of a relationship with the traditional biobank. Perhaps it already feels one-sided, transactional, and unbalanced when trying to fulfill the many needs of a research study design.

7 Factors to Consider When Isolating Specific Cell Types

Isolating unique cell populations for further experimental analyses can answer critical research questions in translational and clinical research—empowering observational and therapeutic studies. A popular approach is to isolate the heterogeneous population of cells in peripheral blood mononuclear cells (PBMCs) using the Ficoll method, followed by further purification to yield unique immune cell subsets, such as activated T cells for further downstream analyses.

Ficoll is not Fickle: Reliable Isolation of PBMCs From Whole Blood

From autoimmune diseases to neurological conditions to pathogenic infections, researchers studying associated immune-mediated mechanisms hope to uncover novel modulatory approaches for therapeutic intervention. To that end, purified human peripheral blood mononuclear cells (PBMCs) represent a heterogeneous population of cells, including B cells (~15%), T cells (~70%), monocytes (~5%), and natural killer (NK) cells (~10%) that can provide valuable phenotypic and functional information.1 But many factors influence PBMC purification quality.

The Challenges of the Lack of Samples in Studies 

Access to samples is essential to researchers’ experiments and assays. This is important when researchers are developing a proof of concept and they need a small set of samples, but it’s also important throughout the duration of studies.  At the beginning of their studies, access to data allows researchers to “get their feet” wet and assess their ability to produce real-world data.

How the Direct-to-Patient Approach Can Streamline your Research Study and Trials

https://vimeo.com/user104376195 The research process can be an inconvenience and a burden for the patient test subject; currently over 40% of test subjects drop out mid-way through the trial. In traditional research models, study participants travel to a medical facility/study-site for screening, baseline, monitoring, and follow-up visits – depending on the study design.

Contributing to Medical Research for a Better Understanding of COVID-19

Sanguine Bioscience, a California-based biotechnology company focused on patient recruitment, sample collection engagement and digital health, has partnered with multiple biotech and pharmaceutical companies, such as Vir Biotechnology and EpiVax, Inc, to facilitate the patient recruitment for over 23 research studies, studies aimed at gaining a better understanding of COVID-19.

Researching COVID-19

We at Sanguine Bioscience have partnered with multiple biotech and pharmaceutical companies, such as Vir Biotechnology and EpiVax, Inc, to facilitate over 23 research studies aimed at gaining a better understanding of COVID-19. Although the overarching goal of this research is to develop treatments and vaccines, valuable information can be obtained about the virus, its patterns of infection, and the effectiveness of community response to the epidemic. 

Sanguine Bio Accelerates Pace in Vaccine Race

Biotech: Blood samples are raw materials for virus research and development. by Amy Stulick, Staff Reporter As pharmaceutical labs race to develop a vaccine for COVID-19, biomaterial for researchers has become increasingly valuable. That works to the advantage of Sanguine Biosciences in Sherman Oaks, which provides blood, tissue, plasma, and other biologic material for R&D.

Overcoming Longitudinal Study Challenges in Medical Research

Longitudinal studies are powerful tools in medical research armamentarium. Researchers gain valuable information following the same group of people with repeated measured variables over time. This type of research provides rates of change of continuous variable(s) over weeks, months, or years allowing researchers to assess patterns in human behavior or cause and effect relationships.